Nadolol belongs to the β-blocker class of blood pressure medications, used to treat hypertension and angina, but it is relatively less commonly used compared to similar drugs like metoprolol (Lopressor). The researchers divided 10 volunteers into two groups, having them take 30 mg of nadolol after drinking plain water or three cups of green tea, respectively, over a period of 14 days. After testing the concentration of the drug in the volunteers' blood, it was found that the concentration of nadolol in the green tea group was 76% lower than in the plain water group. The researchers analyzed that this may be because certain components in green tea disrupt the absorption process of nadolol in the intestines.
Some experts believe that the small sample size of this study means the results still need further verification. However, it is recommended that hypertension patients avoid taking their medication with green tea. If large fluctuations in blood pressure are observed after taking the medication, they should seek medical attention promptly and adjust their treatment plan under a doctor's guidance.